Spermidine and Lung Health: Fibrosis, Airway Epithelium and the Asthma Question (2026)
Lung tissue has an unusual exposure profile. It meets the outside world directly, processes roughly ten thousand litres of air […]
Lung tissue has an unusual exposure profile. It meets the outside world directly, processes roughly ten thousand litres of air […]
The eye is a strange and useful place to test a neuroprotective compound. The retina is central nervous tissue that
Parkinson’s disease is a protein-aggregation disorder, which puts it squarely in the territory where an autophagy inducer should matter. Alpha-synuclein
Alzheimer’s is where the autophagy hypothesis meets its most demanding test. The disease is defined by the accumulation of proteins
Osteoarthritis is an unusually good fit for the autophagy hypothesis, and the research community has noticed. Cartilage is avascular, so
The kidney is an unusually good test case for anything that claims to work through autophagy. It is metabolically expensive,
Muscle is an unusually good test case for autophagy-based supplements, because muscle tissue depends heavily on clearing damaged proteins and
In late 2023 a study in Nature Aging reported that spermidine restored oocyte quality and fertility in aged female mice,
Spermidine labels are unusually easy to misread, and the reason is structural rather than dishonest. Most products are built on
If fasting already switches on autophagy, does adding a supplement that also switches on autophagy do anything extra? It is
Spermidine and fisetin show up in the same longevity stacks, the same podcasts and often the same shopping cart, which
“How long until I notice something” is one of the most common practical questions about any longevity supplement, and it