What Is Spermidine

Discover which foods contain the most spermidine, how this naturally occurring polyamine supports autophagy, and how to increase your intake through diet.

Spermidine, a naturally occurring polyamine, declines as we age. Learn what drives that drop and why it may matter for autophagy and healthy aging.

Learn how the three main polyamines—putrescine, spermidine, and spermine—work in the body, why they decline with age, and where spermidine fits in longevity res

Spermidine induces autophagy primarily by inhibiting the acetyltransferase EP300. Here is what the research actually shows about how this works.